Purpose: The use of adjunctive antimitotics with conventional filterin
g surgery appears to have decreased the need for Molteno implants in g
laucomas with a poor prognosis. We review the current status, results
and complications of Molteno implants. Methods: Review of the literatu
re and practical experience from two university departments of ophthal
mology. Results: Improvements in the design and surgical techniques fo
r Molteno implants have decreased the incidence of over filtration, bu
t this and other complications continue to pose problems. Increased su
ccess rates may be possible if antimitotics are used with Molteno impl
ants. Conclusion: Molteno implants continue to be an option when conve
ntional filtration with or without antimitotics has failed; they conti
nue to be regarded as a last resort for filtration. The use of antimit
otics to increase the success rate of Molteno implants is not proven,
but merits further investigation.