Background: Angiosarcomas are uncommon malignant tumours of vascular e
ndothelium. They frequently affect the face and scalp, but to our know
ledge there are only three reports of eyelid involvement. Methods/resu
lts: We report a case of angiosarcoma arising from the eyelid skin in
a 79-year-old woman. Treatment was surgical with wide excision and sta
ged reconstruction of the defect. Systemic oncological work-up for met
astatic disease was negative. Adjuvant systemic chemotherapy and radio
therapy were considered but were not felt to be of proven benefit and
were not used. The patient died seven months after presentation from a
myocardial infarct. Conclusion: Angiosarcoma should be considered in
the differential diagnosis of unusual or atypical eyelid lesions. Mana
gement is wide surgical excision, although adjuvant systemic therapy s
hould be considered in selected cases in consultation with an oncologi
st.