PHARMACOTHERAPEUTIC RESPONSE OF DST-POSITIVE BORDERLINE PATIENTS

The cases of two borderline patients are presented, dexamethasone supp ression test (DST) positive and refractory to many therapeutic interve ntions and treated successfully with high doses of amitriptyline (225 and 200 mg/day, respectively). During the therapeutic intervention, th e psychopathological condition of the patients was evaluated using Ham ilton's rating scale for depression and a constructed scale based on i tems 11, 12 and 13 (dysphoria, anger, sense of emptiness, boredom, anh edonia) of the diagnostic interview for borderline patients.