SYSTEMIC AA AMYLOIDOSIS INDUCED BY ORAL CONTRACEPTIVE-ASSOCIATED HEPATOCELLULAR ADENOMA - A 13-YEAR FOLLOW-UP

We report a case of a woman who showed hepatic and renal AA amyloidosi s with a liver adenoma associated with the use of oral contraceptives. A nephrotic syndrome secondary to the renal amyloidosis underwent com plete remission 7 years after the withdrawal of oral contraceptive the rapy. Twenty-nine months after the initial presentation, the patient w as admitted with acute upper abdominal pain and abdominal tenderness. The abdominal ultrasound revealed a subphrenic fluid collection, and a presumptive diagnosis of a ruptured hepatic adenoma was made. The liv er adenoma diminished from 8 cm to 1 cm over a 13-year follow up after the discontinuance of oral contraceptive therapy.