SYNTHESIS, SOLUTION CONFORMATION AND BIOLOGICAL PROPERTIES OF 2',3'-DIDEOXY-3'-FLUORO-D-ERYTHRO-PENTOFURANOSIDES OF 2-THIOURACIL AND 2-THIOTHYMINE

Authors
POOPEIKO NE POZNANSKI J DRABIKOWSKA A BALZARINI J DECLERCQ E MIKHAILOPULO IA SHUGAR D KULIKOWSKI T
Citation
Ne. Poopeiko et al., SYNTHESIS, SOLUTION CONFORMATION AND BIOLOGICAL PROPERTIES OF 2',3'-DIDEOXY-3'-FLUORO-D-ERYTHRO-PENTOFURANOSIDES OF 2-THIOURACIL AND 2-THIOTHYMINE, Nucleosides & nucleotides, 14(3-5), 1995, pp. 435-437
Citations number
2
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
14
Issue
3-5
Year of publication
1995
Pages
435 - 437
Database
ISI
SICI code
0732-8311(1995)14:3-5<435:SSCABP>2.0.ZU;2-F
Abstract
The synthesis of the alpha- and beta-anomers of 2',3'-dideoxy-3'-fluor o-2-thiouridine and 2',3'-dideoxy-3'-fluoro-2-thiothymidine via Lewis acid catalysed nucleoside condensation is described. High resolution H -1 NMR data, solution conformations and biological properties are also presented.