THE SYNTHESIS AND BIOLOGICAL-ACTIVITY OF CERTAIN 4'-THIONUCLEOSIDES

Authors
SECRIST JA PARKER WB TIWARI KN MESSINI L SHADDIX SC ROSE LM BENNETT LL MONTGOMERY JA
Citation
Ja. Secrist et al., THE SYNTHESIS AND BIOLOGICAL-ACTIVITY OF CERTAIN 4'-THIONUCLEOSIDES, Nucleosides & nucleotides, 14(3-5), 1995, pp. 675-686
Citations number
20
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
14
Issue
3-5
Year of publication
1995
Pages
675 - 686
Database
ISI
SICI code
0732-8311(1995)14:3-5<675:TSABOC>2.0.ZU;2-P
Abstract
Results are presented on the synthesis and biological activity of seve ral types of 4'-thionucleosides as potential anticancer agents. Detail ed studies on the mechanism of action of 4'-thiothymidine are also pre sented.