SYNTHESIS OF 2'-C-DIFLUOROMETHYL SUBSTITUTED NUCLEOSIDE ANALOGS AS RIBONUCLEOSIDE REPLACEMENTS IN HAMMERHEAD RIBOZYMES

Authors
DUNKEL M REITHER V EBELWILL S LUDWIG J
Citation
M. Dunkel et al., SYNTHESIS OF 2'-C-DIFLUOROMETHYL SUBSTITUTED NUCLEOSIDE ANALOGS AS RIBONUCLEOSIDE REPLACEMENTS IN HAMMERHEAD RIBOZYMES, Nucleosides & nucleotides, 14(3-5), 1995, pp. 799-801
Citations number
10
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
14
Issue
3-5
Year of publication
1995
Pages
799 - 801
Database
ISI
SICI code
0732-8311(1995)14:3-5<799:SO2SNA>2.0.ZU;2-S
Abstract
2'-Difluoromethyl modified nucleoside analogs 4 and 9 have been prepar ed and converted into phosphoramidites for the incorporation into hamm erhead ribozymes.