PHOSPHORAMIDITES OF (RP)-CONFIGURATED AND (SP)-CONFIGURATED ADENOSINEMETHYLPHOSPHONATE DIMERS

Authors
SCHWEITZER M SAMSTAG W ENGELS JW
Citation
M. Schweitzer et al., PHOSPHORAMIDITES OF (RP)-CONFIGURATED AND (SP)-CONFIGURATED ADENOSINEMETHYLPHOSPHONATE DIMERS, Nucleosides & nucleotides, 14(3-5), 1995, pp. 817-820
Citations number
11
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
14
Issue
3-5
Year of publication
1995
Pages
817 - 820
Database
ISI
SICI code
0732-8311(1995)14:3-5<817:PO(A(A>2.0.ZU;2-Q
Abstract
The synthesis of adenosine methylphosphonate dimers, the separation of the diastereomers and the conversion into phosphoramidites is present ed. These dimer building blocks were tested in the solid phase DNA syn thesis of the hairpin decanucleotide 5'-CGCAAAAGCG-3'.