STUDIES ON REACTIONS OF NUCLEOSIDE H-PHOSPHONATES WITH BIFUNCTIONAL REAGENTS .3. FURTHER-STUDIES ON TRANSESTERIFICATION OF NUCLEOSIDE H-PHOSPHONATE DIESTERS WITH AMINO-ALCOHOLS

Authors
SOBKOWSKI M STAWINSKI J SOBKOWSKA A KRASZEWSKI A
Citation
M. Sobkowski et al., STUDIES ON REACTIONS OF NUCLEOSIDE H-PHOSPHONATES WITH BIFUNCTIONAL REAGENTS .3. FURTHER-STUDIES ON TRANSESTERIFICATION OF NUCLEOSIDE H-PHOSPHONATE DIESTERS WITH AMINO-ALCOHOLS, Nucleosides & nucleotides, 14(3-5), 1995, pp. 839-842
Citations number
7
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
14
Issue
3-5
Year of publication
1995
Pages
839 - 842
Database
ISI
SICI code
0732-8311(1995)14:3-5<839:SORONH>2.0.ZU;2-B
Abstract
Reactions of 5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl 2-cyanoethyl ph osphonate with alcohols, amines and amino alcohols in pyridine are des cribed. Transesterification was found to be faster than beta-eliminati on of 2-cyanoethyl group.