Ia. Mikhailopulo et al., SYNTHESIS AND USE OF (2',5')OLIGOADENYLATE TRIMERS MODIFIED AT THE 2'-TERMINUS IN KIDNEY-TRANSPLANTATION IN RABBITS AND MONKEYS, Nucleosides & nucleotides, 14(3-5), 1995, pp. 1105-1108
Two core trimers, (2',5')A(2)A(RA) and (2',5')A(2)A(LA), with 9-(2,3-a
nhydro-beta-D-ribofuranosyl)-adenine (A(RA)) and its lyxo-isomer (A(LA
)) at the 2'(3')-terminus, respectively, were synthesized and their us
e as immunosuppressors in kidney transplantation in animals was invest
igated.