Objectives: a) to validate the structure of the Sickness Impact Profil
e scale (SIP) when applied to intensive care patients after discharge
from the hospital; b) to explore the influence of age upon the various
components of quality of life. Design: Prospective study. Setting: Pa
tients admitted to 36 Dutch ICUs. Methods: 6247 patients out of 13000
consecutive admissions to the ICUs answered a SIP questionnaire 6 mont
hs after discharge from the hospital. The 3655 returned questionnaires
were analyzed after aggregating the respondents into 6 age groups: fr
om group 1: 17-29 up to group 4: >70 years of age. Intervention: Self-
administration of SIP one year after discharge, measuring 5 independen
t categories (IC) and two dimensions: physical (PD) and psychosocial (
PSD). Results: The total SIP-score oscillated between 5.8 +/- 8.2 (gro
up I) and 10.5 +/- 9.5 (group 4). Group 3 had also a high score (9.4 /- 11.2). Overall, the quality of life of patients was dominated by dy
sfunction on the categories composing the physical dimension, with exc
eption of patients with ages between 30 and 50 years, in which dysfunc
tion on the categories composing the psychosocial dimension was domina
nt. The structure of the SIP in the study was similar to that describe
d to the original instrument. Conclusions: The study validated the use
of the SIP QOL-instrument on patients after intensive care. Age influ
enced consistently the various components of quality of life.