S. Tejayadi et M. Cheryan, LACTIC-ACID FROM CHEESE WHEY PERMEATE - PRODUCTIVITY AND ECONOMICS OFA CONTINUOUS MEMBRANE BIOREACTOR, Applied microbiology and biotechnology, 43(2), 1995, pp. 242-248
The economics of incorporating membrane modules in several steps in th
e conversion of whey permeate to lactic acid was studied. Membrane rec
ycle fermenters operating at a cell concentration of 40 g l(-1) result
ed in a productivity of 22.5 g l(-1)h(-1) with a lactate concentration
of 89 g l(-1) and a yield of 0.89. The membrane units (reverse osmosi
s for preconcentrating whey permeate, hollow-fiber ultrafiltration for
clarification and for cell recycling) contribute about 28% of the tot
al fixed capital costs and less than 5% of the operating cost. The two
largest costs are whey transportation and yeast extract, contributing
about 35% and 38% to the total product cost of US $ 0.98/kg 85% lacta
te. Without these two costs; unpurified lactate could be produced for
$ 0.27/kg.