M. Eysker et al., EFFICACY OF MICHELS DOSE-AND-MOVE SYSTEM AGAINST DICTYOCAULUS-VIVIPARUS INFECTIONS IN CATTLE USING MOXIDECTIN AS ANTHELMINTIC, Veterinary parasitology, 58(1-2), 1995, pp. 49-60
Two grazing experiments were performed to study the effect of moxidect
in in a 'dose and move' system on Dictyocaulus viviparus infections in
calves. In the first experiment, three groups of four calves were exp
erimentally infected with 20 larvae of D. viviparus 7 weeks before mox
idectin treatment of two of these groups, A sufficient suppression of
Dictyocaulus infections was observed in a 'dose and move' group, but a
lso in a group which stayed on contaminated pasture after treatment. I
n contrast, high faecal larval counts and lungworm disease were observ
ed in July-August in a nontreated pasture control group, Development o
f immunity against lungworm was sufficient in all three groups on past
ure, In the second experiment, four out of 16 calves, including two gr
oups of six calves and four tracer calves, were experimentally infecte
d with 20 larvae of D. viviparus 7 weeks before moxidectin treatment c
ombined with a move of one of the groups, No lungworm disease was obse
rved in this 'dose and move' group, In a pasture control group high fa
ecal larval counts and severe clinical disease were observed in August
-September and one calf had to be euthanized. Although a mean burden o
f 129 immature lungworms was present at the time of treatment, develop
ment of immunity appeared to be low in the 'dose and move' group, In c
ontrast, high levels of immunity had developed in the pasture control
group.