Water extracts from the brackishwater clam (Corbicula japonica) were f
ound to be lethal to mice upon i.v. injection. Muscular tissues (foot
muscle, adductor muscle, mantle muscle, mantle and siphon) were all to
xic while gill and viscera (mid-gut gland, testis and ovary) were nont
oxic; the highest toxicity was observed with foot muscle. The toxin wa
s judged to be a thermolabile, basic protein with a mol. wt of about 1
3,000.