Fifty open tibial fractures with circumferential cortical bone loss we
re reviewed. Prospective treatment protocols included fracture stabili
zation with repeated irrigation and debridement followed by wound cove
rage. Bony stabilization was accomplished using external fixators, sma
ll diameter unreamed interlocking nails, and, in rare instances, plate
fixation. Bone graft procedures included posterolateral bone graft, e
levation of the free flap or direct anterolateral grafting, bone trans
port techniques, and free vascularized fibula transfer. Average follow
up was 18 months (range, 9-40 months). The index graft procedure was u
sed in 30 patients (60%) for fracture healing. The rate of union was 9
8%, with an average total treatment time of 42.4 weeks (range, 23-80 w
eeks). Malunion was more likely to develop in patients treated with ex
ternal fixation and posterolateral bone graft (p = 0.007). Intramedull
ary nails with direct bone grafting had shorter times to union and sho
rter total treatment times. The use of free vascular fibular transfers
in acute injuries was not successful. Good results were obtained with
bone transport techniques. Developing a healthy soft tissue envelope
before reconstruction of these injuries is important. Techniques of re
construction had no correlation to the development of nonunion or infe
ction. They were valuable in determining malunion and total treatment
time. These data confirm that carefully staged reconstruction leads to
successful outcomes.