D. Sassi et al., CYTOFLUOROMETRIC EVIDENCE FOR DIFFERENTIAL GENOME ENDOREPLICATION IN THE CLUSTER NEURONS OF LOPHIUS-PISCATORIUS L (OSTEICHTHYES, LOPHIIFORMES), European journal of histochemistry, 39(2), 1995, pp. 117-126
Quantitative microfluorometric evaluation indicated that, in Lophius p
iscatorius, the DNA content of large neurons of a cluster located at t
he boundary between the medulla oblongata and the spinal cord varied f
rom 4C to more than 5000C. This finding must be considered exceptional
for the nervous system of Vertebrates. DNA contents were correlated t
o both nuclear and animal size. Utilization of AT and GC specific fluo
rochromes showed that the increase in DNA content is due to differenti
al genome amplification involving GC-rich DNA sequences.