INCIDENCE OF PENILE PAIN AFTER INJECTION OF A NEW FORMULATION OF PROSTAGLANDIN-E1

Purpose: We determined the incidence of pain with injection of a new f ormulation of prostaglandin E1. Materials and Methods: A total of 63 s ubjects with erectile dysfunction underwent treatment with the new for mulation of prostaglandin E1. Evidence of pain associated with injecti on was obtained by questionnaire and through questioning. Results: A t otal of 451 injections was given to 63 subjects in the office, with 16 episodes (3.5%) of pain in 10 (15.9%). Then, 680 injections were perf ormed by 38 subjects at home, with 15 episodes (2.2%) of pain in 8 (21 %). Pain was not dose related. Conclusions: The new formulation of pro staglandin E1 is less likely to be associated with pain compared with alcohol based formulations.