CHEMOENZYMATIC SYNTHESIS OF TRANS-4,5-DIHYDROXYCYCLOPENT-2-ENONES - CONVERSION TO D-1-DEOXYNOJIRIMYCIN

Authors
JOHNSON CR NERURKAR BM GOLEBIOWSKI A SUNDRAM H ESKER JL
Citation
Cr. Johnson et al., CHEMOENZYMATIC SYNTHESIS OF TRANS-4,5-DIHYDROXYCYCLOPENT-2-ENONES - CONVERSION TO D-1-DEOXYNOJIRIMYCIN, Journal of the Chemical Society, Chemical Communications, (11), 1995, pp. 1139-1140
Citations number
33
Categorie Soggetti
Chemistry
Journal title
Journal of the Chemical Society, Chemical Communications → ACNP
ISSN journal
00224936
Issue
11
Year of publication
1995
Pages
1139 - 1140
Database
ISI
SICI code
0022-4936(1995):11<1139:CSOT-C>2.0.ZU;2-W
Abstract
5-Bis(tert-butyldimethylsilyloxy)cyclopent-2-enone 8 and (4R,5S)-trans -4,5-di(benzyloxy)cyclopent-2-enone 20 are prepared by equilibration o f the corresponding cis derivatives; enone 8 is transformed into the g lucosidase inhibitor, D-1-deoxynojirimycin 14.