Condensation of 4-methoxy-2,6-dimethylbenzaldehyde with Meldrum's acid
, and flash vacuum pyrolysis of the condensation product (12) gave in
almost quantitative yield 7-methoxy-5-methyl-2-naphthol (9). This naph
thol is a precursor of the title l-carboxylic acid (6),(1) an intercal
ating moiety of enediyne and other antibiotics.