Background: Managing filtration surgery bleb leaks can be difficult as
well as frustrating. Treatment options traditionally have included aq
ueous suppressants, patching, and bleb compression devices. Previously
, if conservative management failed, surgical revision was considered.
Methods: Six patients with thin avascular blebs and discrete leaking
holes (2 had had full-thickness procedures, 4 had had trabeculectomy w
ith mitomycin C) underwent subconjunctival injection of approximately
1 ml of whole autologous blood. Injections were made just lateral and
just medial to the domed cystic elevation of the blebs. Results: Five
of six eyes were leak-free by the second day after the procedure. No c
omplications occurred. After 4 to 12 months of follow-up, four eyes ar
e currently leak-free. In these eyes, intraocular pressure is between
8 and 12 mmHg. Conclusion: Subconjunctival peribleb injection of autol
ogous blood may be a safe and helpful adjunct in treating selected pos
tfiltration surgery bleb leaks.