Ed. Donnenfeld et al., CONTROLLED EVALUATION OF A BANDAGE CONTACT-LENS AND A TOPICAL NONSTEROIDAL ANTIINFLAMMATORY DRUG IN TREATING TRAUMATIC CORNEAL ABRASIONS, Ophthalmology, 102(6), 1995, pp. 979-984
Background: Treating traumatic corneal abrasions is a common problem f
or the ophthalmologist. Traditional management has been the use of a p
ressure patch. Three different therapeutic modalities were evaluated f
or their efficacy in treating traumatic corneal abrasions. Methods: Fo
rty-seven consecutive patients with traumatic corneal abrasions were r
andomized prospectively in a single-masked, controlled clinical trial
which compared the efficacy of (1) pressure patching, (2) a bandage co
ntact lens, and (3) a bandage contact lens with a topical nonsteroidal
anti-inflammatory drug (0.5% ketorolac tromethamine). Results: There
was no significant difference in the healing time of the three groups.
However, psychometric analysis showed a significant decrease in pain
in the group that received a bandage-contact lens with a topical nonst
eroidal anti-inflammatory drug. There was a significant difference in
the ability to return to normal activities in both contact lens groups
compared with the pressure-patch group. There was no significant diff
erence among the three groups with respect to photophobia, redness, oc
ular irritation, headache, or tearing. Conclusion: Use of a bandage co
ntact lens significantly shortens the time required for a patient to r
eturn to normal activities. Moreover, addition of a nonsteroidal antii
nflammatory drug to a treatment regimen significantly decreases the pa
in associated with traumatic corneal abrasions. Use of a bandage conta
ct lens with a topical nonsteroidal anti-inflammatory may prove to be
an effective adjunct in treating traumatic corneal abrasions.