Creatine phosphate allows high rates of adenosine triphosphate resynth
esis to occur in muscle and therefore plays a vital role in the perfor
mance of high-intensity exercise. Recent studies have shown that feedi
ng large amounts of creatine (typically 20g per day for 5 days) increa
ses muscles total creatine (and phosphocreatine) content. The extent o
f the increase that is normally observed is inversely related to the p
resupplementation level. Vegetarians, who have a very low dietary crea
tine intake, generally show the largest increases. Creatine supplement
ation has been shown to increase performance in situations where the a
vailability of creatine phosphate is important; thus, performance is i
mproved in very high-intensity exercise and especially where repeated
sprints are performed with short recovery periods. Creatine supplement
ation is widely practiced by athletes in many sports and does not cont
ravene current doping regulations. There are no reports of harmful sid
e effects at the recommended dosage.