PERCUTANEOUS-ABSORPTION OF METHYL NICOTINATE

Authors
LAFFORGUE C EYNARD I FALSON F WATKINSON AC HADGRAFT J
Citation
C. Lafforgue et al., PERCUTANEOUS-ABSORPTION OF METHYL NICOTINATE, International journal of pharmaceutics, 121(1), 1995, pp. 89-93
Citations number
2
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
International journal of pharmaceutics → ACNP
ISSN journal
03785173
Volume
121
Issue
1
Year of publication
1995
Pages
89 - 93
Database
ISI
SICI code
0378-5173(1995)121:1<89:POMN>2.0.ZU;2-U
Abstract
The percutaneous absorption of methyl nicotinate was measured in vitro across hairless rat skin. The methyl nicotinate was applied in vehicl es containing propylene glycol dipelargonate, Labrafac Hydrophile(R) a nd Transcutol(R). In vitro experiments were analysed using solutions t o Fick's laws of diffusion in order to determine permeation parameters .