G. Fardella et al., QUANTITATIVE-ANALYSIS OF FLUOROQUINOLONES BY H-1-NMR AND F-19-NMR SPECTROSCOPY, International journal of pharmaceutics, 121(1), 1995, pp. 123-127
H-1- and F-19-NMR assay of pefloxacin (I), norfloxacin (II) and ofloxa
cin (III) in some pharmaceutical forms has been developed. The method,
based on the integration of appropriate signals of both analytes and
internal standards, is simple, rapid, precise, and accurate, and can b
e used for quality control of these drugs.