PSEUDOPORPHYRIA DUE TO NAPROXEN - A CLUSTER OF 3 CASES

Pseudoporphyria is a photo-induced blistering disorder with increased skin fragility, caused among others by nonsteroidal antiinflammatory d rugs. Lesions heal with scarring and milia. Porphyrin screen studies a re normal in this disease. Histology and immunofluorescence resembles porphyria cutanea tarda. In this report we describe a cluster of three cases of naproxen-induced pseudoporphyria, and review briefly previou sly reported cases induced by naproxen. The majority of reported cases involve children. Physicans should be aware of this reversible skin d isorder.