A PC-PROGRAM FOR THE ANALYSIS OF ELECTROP HYSIOLOGICAL SIGNALS RECORDED FROM THE MAMMALIAN EYE

Background Electrophysiological measurements in the mammalian eye in v ivo or in vitro, i.e. in the arterially perfused cat eye, require stor age and analysis of a large amount of data: light-evoked signals, incl uding the electroretinogram (ERG) and the optic nerve response (ONR) a re stimulus-related and have to be measured in a triggered mode, where as the DC-standing potential and now rate of perfusion medium should b e measured continuously. Method and result In order to facilitate the analysis of these various signals, we developed a computer program, th at allows an on-line data analysis and a trend indication for pharmaco logically induced changes in signal size as well as efficient storage. The flexible system is based on a ''labview'' program, the applicatio n and efficiency of which are discussed.