We report on an asymmetric maculopapular exanthem of early childhood.
One hundred eighty seven patients (111 girls, 76 boys) were examined o
ver a four-year period, mainly in winter and spring. The first skin le
sions appeared on the trunk or in the large flexures of the limbs. The
y spread centrifugally, often to the contralateral side, over two to f
our weeks, and disappeared with slight itching and moderate desquamati
on within another two to four weeks. Virologic studies were carried ou
t in 34 cases; parainfluenzavirus 2, parainfluenzavirus 3, and adenovi
ral infection were diagnosed in two patients each. The chances of a ca
usal relation between the viral infection and the skin symptoms were s
light; only an incidental connection is likely to exist between the sk
in disorders and the viral infection.