A newborn boy had junctional epidermolysis bullosa, duodenal obstructi
on, and gastric infarction, a newly described combination that extends
the spectrum of gastrointestinal findings associated with junctional
epidermolysis bullosa. The infant underwent feeding jejunostomy, but d
ied 16 days after birth. This report emphasizes the need for gastroint
estinal assessment in any neonate suspected of having epidermolysis bu
llosa, especially if the pregnancy was complicated by polyhydramnios.