NOSOCOMIAL SPREAD OF HEPATITIS-B VIRUS (HBV) IN A HEMODIALYSIS UNIT CONFIRMED BY HBV DNA-SEQUENCING

Authors
ROLL M NORDER H MAGNIUS LO GRILLNER L LINDGREN V
Citation
M. Roll et al., NOSOCOMIAL SPREAD OF HEPATITIS-B VIRUS (HBV) IN A HEMODIALYSIS UNIT CONFIRMED BY HBV DNA-SEQUENCING, The Journal of hospital infection, 30(1), 1995, pp. 57-63
Citations number
15
Categorie Soggetti
Infectious Diseases
Journal title
The Journal of hospital infection → ACNP
ISSN journal
01956701
Volume
30
Issue
1
Year of publication
1995
Pages
57 - 63
Database
ISI
SICI code
0195-6701(1995)30:1<57:NSOHV(>2.0.ZU;2-E
Abstract
An outbreak of hepatitis B virus (HBV) infection in a haemodialysis un it is described. Four patients in the unit contracted subclinical HBV infection within three months. DNA sequence analysis of the S gene of HBV isolates from chronic carriers and newly infected patients in the unit aided in tracing possible transmission pathways. Three newly infe cted patients had received partial or complete HBV vaccination previou sly. HBV was rapidly cleared from all three although the anti-HBs titr e had not reached 10 IU L(-1) in any of them at the time of infection.