EPIDEMIOLOGY OF PSEUDOMONAS-AERUGINOSA KERATITIS IN CONTACT-LENS WEARERS

This study evaluated the epidemiology of Pseudomonas aeruginosa kerati tis in contact lens (CL) wearers; the relationships between CL storage case contamination and CL hygiene practice and between CL hygiene and the development of keratitis. Sixteen CL wearers with keratitis were compared with 44 asymptomatic controls. ens hygiene practice was asses sed and CL care materials, domestic water sites and endogenous sites w ere evaluated microbiologically. Poor CL hygiene was not associated wi th Ps, aeruginosa keratitis. There was an association between keratiti s and bacterial contamination of the CL and storage case (P<0.0005). L ens and storage case contamination were not significantly associated w ith poor hygiene. No domestic or endogenous source for Ps. aeruginosa was found. Causative organisms may be derived from other sources, but CLs and CL storage cases provide a favourable environment for Ps. aeru ginosa colonization. Changing the CL care environment to one less favo urable for Ps. aeruginosa may help to eliminate this problem.