COMMON VARIABLE IMMUNODEFICIENCY IN A RENAL-TRANSPLANT PATIENT WITH SEVERE RECURRENT BACTERIAL-INFECTION - A CASE-REPORT AND REVIEW OF THE LITERATURE

The second reported case of common variable immunodeficiency (acquired agammaglobulinemia) after renal transplantation is presented, Agammag lobulinemia presumably resulted from long-standing immunosuppression. This case and our review of the literature indicate that agammaglobuli nemia is a rare event after transplantation but can be treated success fully with intravenous immunoglobulin. Additionally, hypogammaglobulin emia occurs frequently after transplantation and should be monitored a nd treated in appropriate clinical situations. The treatment of our pa tient with intravenous immunoglobulin also suggests that patients with common variable immunodeficiency can undergo renal transplantation. ( C) 1995 by the National Kidney Foundation, Inc.