Alcohol consumption clearly reduces risk of cardiovascular disease (CV
D) in populations throughout the world and may contribute to lower rat
es of CVD among residents of Mediterranean countries. In addition, ove
rall mortality rates are generally slightly lower among moderate drink
ers than among abstainers. However, several studies have linked alcoho
l consumption (even amounts equivalent to two drinks daily) to increas
ed rates for certain cancers, especially breast cancer in women. A Med
iterranean diet, which is high in fruit, vegetables, and grains, also
typically includes one to two drinks per day. Whether one to two drink
s adversely affect cancer incidence in the presence of a Mediterranean
diet has not been fully explored. With the evidence currently availab
le, we conclude that alcohol, when consumed responsibly in most popula
tions, is an important component of the Mediterranean diet and a compo
nent of a healthy lifestyle.