PHASE-BEHAVIOR OF MIXTURES OF CHOLESTEROL AND SATURATED PHOSPHATIDYLGLYCEROLS

Authors
BOROCHOV N WACHTEL EJ BACH D
Citation
N. Borochov et al., PHASE-BEHAVIOR OF MIXTURES OF CHOLESTEROL AND SATURATED PHOSPHATIDYLGLYCEROLS, Chemistry and physics of lipids, 76(1), 1995, pp. 85-92
Citations number
24
Categorie Soggetti
Biology
Journal title
Chemistry and physics of lipids → ACNP
ISSN journal
00093084
Volume
76
Issue
1
Year of publication
1995
Pages
85 - 92
Database
ISI
SICI code
0009-3084(1995)76:1<85:POMOCA>2.0.ZU;2-U
Abstract
The interaction of cholesterol with a series of saturated phosphatidyl glycerols was investigated using differential scanning calorimetry and X-ray diffraction. We find that the miscibility of cholesterol in pho sphatidylglycerol bilayers is lower than in the corresponding phosphat idylcholine bilayers and decreases with increasing acyl chain length o f the phospholipid. The influence of the negative charge of the phosph atidylglycerol on cholesterol miscibility is discussed.