T. Nishida et al., THE SERUM LEVEL OF MANGANESE SUPEROXIDE-DISMUTASE IN PATIENTS WITH OVARIAN EPITHELIAL MALIGNANCY, Oncology Reports, 2(4), 1995, pp. 643-646
The serum level of a scavenging enzyme, manganese superoxide dismutase
(MnSOD) was examined in 95 patients with ovarian epithelial malignanc
y. The MnSOD values were variable according to the differences of surg
ical stage, histologic type and histological grade. Factors affecting
the MnSOD level were statistically analyzed. The stage and histologic
type were less effective than the histological grade in determining th
e serum MnSOD value. The level increased significantly in accordance w
ith the elevation of grade. Although the mechanism remains unclear, th
e MnSOD determination may be useful in predicting the histological gra
de of ovarian carcinoma.