MASS-SPECTROMETRY OF CYANOCOBALAMINE, GLUCOSE AND RAFFINOSE IN THE SOLID-STATE AND ON A DISPERSE OXIDE SURFACE

The biologically active systems were synthesized by adsorption of vita min B12, glucose and raffinose on an ultrafine oxide surface and studi ed by means of thermal analysis and temperature-programmed mass spectr ometry. It is shown that adsorption of cyanocobalamine (B12) on the si lica surface transformed the propionamide group to a weakly bound form . The role of the charged cobalt atom and of the propionamide and benz imide groups in the adsorption mechanism is discussed. Experimental da ta were obtained confirming the stable adsorption of glucose and raffi nose on an ultrafine pyrogenic silica surface modified by amino groups .