CUMULATIVE CONCEPTION RATE FOLLOWING INTRAUTERINE ARTIFICIAL-INSEMINATION WITH HUSBANDS SPERMATOZOA - INFLUENCE OF HUSBANDS AGE

This paper presents the analysis of 901 cycles of intrauterine artific ial insemination with the husbands spermatozoa (AIHIU) in 274 couples who obtained 80 pregnancies. The cumulative pregnancy rate after three cycles of AIHIU was 22% and reached 39% after six cycles. Univariate analysis disclosed two factors of poor prognosis: duration of infertil ity >3 years (P = 0.01) and husband's age (P = 0.03). Multivariate ana lysis revealed that the most significant factor contributing to a decr eased likelihood of pregnancy was the age of the husband (P = 0.01), t hen duration of infertility and dysovulation. The wife's age greater t han or equal to 35 years did not appear to be of poor prognostic value when taking into consideration the three other factors.