A. Evoli et al., FAMILIAL AUTOIMMUNE MYASTHENIA-GRAVIS - REPORT OF 4 FAMILIES, Journal of Neurology, Neurosurgery and Psychiatry, 58(6), 1995, pp. 729-731
Four families each with two patients with autoimmune myasthenia gravis
or related conditions are reported. All clinical forms of myasthenia
gravis were represented and different disease types were found within
the same family. Either one or two generations could be affected and n
o association with a single HLA haplotype was found. The frequency of
familial autoimmune myasthenia gravis is very low and the genetic fact
ors involved seem to be different from MHC genes.