L. Kolodzieyski et al., LYMPH-NODE MACROPHAGES AFTER APPLICATION OF GLUCAN IN CALVES - AN ELECTRON-MICROSCOPIC STUDY, Journal of veterinary medicine. Series A, 42(2), 1995, pp. 131-138
The present study was designed to reveal by electron microscopy the dy
namics of degradation processes of glucan after phagocytosis in the ly
mph nodes. A soluble form of glucan at a dosage of 50 mg/kg body weigh
t induced a distinct phagocytic activity. On day 7, after stimulation
of the lymph nodes, glucan was gradually degraded through fibrillar, p
articular components, and finally into a light microscopically invisib
le content. The ingestive capacity of macrophages was higher compared
to phagocytic ability of the sinus-lining and reticular cells. On day
30, after stimulation, the lymph nodes indicated restoration of the ar
chitecture of their medullary pulp.