SELECTIVE CATION-BINDING WITH CIS,CIS-1,3,5-TRIOXYCYCLOHEXYL BASED LIGANDS - APPLICATION TO ION-TRANSPORT AND ELECTROCHEMICAL DETECTION ANDASSESSMENT OF COMPLEXATION BY ELECTROSPRAY MASS-SPECTROMETRY

Authors
GOODALL M KELLY PM PARKER D GLOE K STEPHAN H
Citation
M. Goodall et al., SELECTIVE CATION-BINDING WITH CIS,CIS-1,3,5-TRIOXYCYCLOHEXYL BASED LIGANDS - APPLICATION TO ION-TRANSPORT AND ELECTROCHEMICAL DETECTION ANDASSESSMENT OF COMPLEXATION BY ELECTROSPRAY MASS-SPECTROMETRY, Perkin transactions. 2, (1), 1997, pp. 59-69
Citations number
38
Categorie Soggetti
Chemistry Physical","Chemistry Inorganic & Nuclear
Journal title
Perkin transactions. 2 → ACNP
ISSN journal
03009580
Issue
1
Year of publication
1997
Pages
59 - 69
Database
ISI
SICI code
0300-9580(1997):1<59:SCWCBL>2.0.ZU;2-8
Abstract
The synthesis is reported of two sets of oxa-amide ionophores based on 2-phenylglycerol and cis,cis-cyclohexane-1,3,5-triol, with ligand coo rdination numbers of four, five and six, Ionophores based on the hexad entate cyclohexyl triamide 9 show excellent Na+/K+ selectivity (-log K -Na,K(pot) = 3.1), and the pentadentate analogue 10 shows good Li+/Na selectivity (-log K-Li,Na(pot) = 2.2), solution NMR and liquid-liquid extraction studies confirmed the formation of 1:1 complexes and IR st udies pinpointed the presence of amide binding, Ligands based on 2-phe nylglycerol exhibited good Ca2+ selectivity which was highest for the hexadentate triamide, 6, Detailed ESMS studies revealed similar trends in ion-binding, performed under controlled conditions.