THE NEW SYNDROME OF CONGENITAL HYPOPARATHYROIDISM ASSOCIATED WITH DYSMORPHISM, GROWTH-RETARDATION, AND DEVELOPMENTAL DELAY - A REPORT OF 6 PATIENTS

We describe six children of Arab origin with a syndrome of congenital hypoparathyroidism, severe growth retardation, developmental delay, an d dysmorphism. The most prominent dysmorphic features were microcephal y, facial and dental anomalies, and small hands and feet. Bone age was markedly retarded. Neither immunological nor chromosomal abnormalitie s were found. Insulin-like growth factor-1 serum levels, measured in t wo patients, were abnormally low.