Ma. Teillet et al., REFLEX EPILEPSY OF THE FOWL AND ITS TRANSFER TO NORMAL CHICKENS BY BRAIN EMBRYONIC GRAFTS, Italian journal of neurological sciences, 16(1-2), 1995, pp. 83-89
The genetic photosensitive epilepsy of the Fayoumi chicken was transfe
rred to normal chickens by in situ grafts at 2 days of incubation, of
both the prosencephalic and mesencephalic brain vesicles taken from ep
ileptic embryos, However, mesencephalic graft is sufficient to allow c
onvulsions under sound stimulation, Typical EEG patterns are recorded
in chimeras having the prosencephalon plus or not the mesencephalon, W
e conclude that, in this mutant the whole neural tissue is affected, b
ut the seizure generator is localized inside the mesencephalon, and sp
ecific sensory pathways are necessary for seizures to occur.