Approximately 80% of breast biopsies are performed for what proves to
be a benign process. The patients who undergo these procedures should
continue screening with breast physical examination and mammography. T
he long-term impact of breast biopsy on these screening modalities has
not been well studied. We performed a prospective, follow-up evaluati
on in 63 patients who underwent needle localization biopsy with benign
histology at our institution between 6 and 7 years ago. This evaluati
on consisted of a directed history, breast physical examination, and f
ollow-up mammogram. Two patients (3%) had undergone mastectomy for an
interval breast cancer; 17 others (28%) had undergone subsequent biops
ies. No patient had changes on physical examination of the biopsy site
. All mammograms were evaluated as normal or as having benign abnormal
ities. Excisional breast biopsy does not generally produce long-term c
hanges affecting the interpretation of breast physical examination or
mammography. (C) 1995 Wiley-Liss, Inc.