Oral lichen planus (LP) is a relatively common disorder of unknown aet
iology. Oral LP occurs most often on the buccal mucosa, but the gingiv
ae, tongue, floor of the mouth, retromalar pads and lips may also be a
ffected. Usually, patients have multiple sites of involvement, We repo
rt a 44-year-old patient with a 3-year history of isolated swelling of
the lower lip, erosions and crusting. Histology of a biopsy from the
lip revealed features of LP; Oral treatment with acitretin and low-dos
e steroid led to complete resolution of the lesions within 10 weeks. T
his is the first well-documented case of isolated LP of the lip. Diagn
ostic difficulties and differential diagnosis are reviewed.