The surgical, ophthalmological, and dermatological applications of hig
h power lasers are well known and easily understood. What is neither a
s well known nor as easily understood is that lasers at powers that ar
e orders of magnitude smaller have also been used in the laboratory an
d clinic for nearly 30 years to modulate cell function, lessen pain, a
nd accelerate healing of soft tissue injuries. This article analyzes t
he rationale of this approach, examines the utility of laser therapy i
n its most common clinical applications, reviews and synthesizes the f
indings, and concludes that although laboratory findings seem authenti
c, clinical utility remains unestablished. (C) 1995 Wiley-Liss, Inc.