Chronic post-thoracotomy pain (CPP) is a vexing clinical problem whose
management has received scant attention. In order to identify the ris
k factors associated with CPP and determine the optimal treatment, the
records of 238 consecutive patients who underwent thoracotomy were re
viewed. CPP was defined as discomfort requiring the regular administra
tion of analgesics that continued more than three months following sur
gery. CPP was present in 25 (11%) patients: 10/20 (50%) chest wall res
ections, 5/25 (20%) pleurectomies, 10/193 (5%) pulmonary resections. A
mong the 23 patients who required preoperative narcotics, 12 (52%) dev
eloped CPP. Improved pain control and decreased narcotic use was achie
ved via the administration of nonsteroidal anti-inflammatory medicatio
n and tricyclic anti-depressants. In addition, 10/25 patients required
11 pain procedures: trigger-point injection, intercostal blocks, inje
ctions of epidural steroids, stellate ganglion block. Recurrent pain o
ccurred in 20 patients following initial control. All were found to ha
ve tumor regrowth. We conclude that CPP occurs more commonly following
chest-wall resection and pleurectomy, and that preoperative narcotic
use is a predictor of CPP. Worsening pain. following initial relief sh
ould prompt a vigorous search for recurrent cancer.