Renal angiomyolipomas, the most familiar of the renal hamartomas, are
well known to radiologists, despite being uncommon and of limited clin
ical importance, because angiomyolipomas represent one of the few lesi
ons for which a specific diagnosis can be achieved on the basis of rad
iologic findings in the majority of cases, Because of the diversity in
the relative amounts of various cellular components and because of th
e occasional association with acute hemorrhage, the radiologic feature
s of angiomyolipomas can be somewhat varied. At sonography, angiomyoli
pomas appear echogenic with acoustic shadowing, At computed tomography
(CT), these lesions typically appear as well-marginated, small (<5 cm
in size), cortical masses of predominantly fat attenuation with heter
ogeneous soft-tissue attenuation interspersed throughout, Some angiomy
olipomas are larger and poorly marginated because of hemorrhage, Typic
al angiomyolipomas are largely composed of fat; those uncommon tumors
without demonstrable fat cannot be radiologically distinguished from r
enal cell carcinoma. Renal leiomyoma, a lesion that pathologically ove
rlaps with angiomyolipoma to some degree, has a quite different imagin
g appearance tie, homogeneous, without detectable fat) that cannot be
distinguished from malignant renal lesions.