DESIGN AND SYNTHESIS OF D-RIBOFURANOAMIDRAZONES AS INHIBITORS OF NUCLEOSIDE PROCESSING ENZYMES

Authors
BOUTELLIER M GANEM B HORENSTEIN BA SCHRAMM VL
Citation
M. Boutellier et al., DESIGN AND SYNTHESIS OF D-RIBOFURANOAMIDRAZONES AS INHIBITORS OF NUCLEOSIDE PROCESSING ENZYMES, Synlett, (5), 1995, pp. 510-512
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
5
Year of publication
1995
Pages
510 - 512
Database
ISI
SICI code
0936-5214(1995):5<510:DASODA>2.0.ZU;2-1
Abstract
The five-membered amidrazones 1-4, designed as stable mimics of the ri bofuranosyl cation, are potent competitive inhibitors of nucleoside hy drolase from Crithidia fasciculata.