A CONVENIENT SYNTHESIS OF VERSATILE SIDE-CHAIN INTERMEDIATES FOR CARBAPENEM ANTIBIOTICS

Authors
KAWAMOTO I ENDO R ISHIKAWA K KOJIMA K MIYAUCHI M NAKAYAMA E
Citation
I. Kawamoto et al., A CONVENIENT SYNTHESIS OF VERSATILE SIDE-CHAIN INTERMEDIATES FOR CARBAPENEM ANTIBIOTICS, Synlett, (5), 1995, pp. 575-577
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
5
Year of publication
1995
Pages
575 - 577
Database
ISI
SICI code
0936-5214(1995):5<575:ACSOVS>2.0.ZU;2-E
Abstract
A useful synthesis of(2S, 4S)-4-(4-methoxybenzylthio)-1-substituted py rrolidinecarboxylic acid is reported. At each step, practically all co mpounds were obtained in crystalline form by simple procedure without column chromatograpy. These compounds are versatile side-chain precurs ors to carbapenem antibiotics.