SEPARATION OF BIOACTIVE QUADRI-TERPENIC ACIDS FROM THE FRUIT OF LIGUSTRUM-LUCIDUM AIT BY HIGH-SPEED COUNTERCURRENT CHROMATOGRAPHY

Authors
DU QZ XIONG XP ITO Y
Citation
Qz. Du et al., SEPARATION OF BIOACTIVE QUADRI-TERPENIC ACIDS FROM THE FRUIT OF LIGUSTRUM-LUCIDUM AIT BY HIGH-SPEED COUNTERCURRENT CHROMATOGRAPHY, Journal of liquid chromatography, 18(10), 1995, pp. 1997-2004
Citations number
8
Categorie Soggetti
Chemistry Analytical
Journal title
Journal of liquid chromatography → ACNP
ISSN journal
01483919
Volume
18
Issue
10
Year of publication
1995
Pages
1997 - 2004
Database
ISI
SICI code
0148-3919(1995)18:10<1997:SOBQAF>2.0.ZU;2-I
Abstract
High-speed countercurrent chromatography (HSCCC) was used for the sepa ration of quadri-terpenic acids from the fruit of Ligustrum lucidum Ai t using a two-phase solvent system composed of hexane/ethyl acetate/me thanol/water (3:6:2:1, v/v). From 250mg of the crude extract, the meth od yielded 87 mg of oleanolic acid at 91.5% purity and 58 mg of ursoli c acid at 93.2% purity in about 2.5 h.