ONE ARTIFICIAL-INSEMINATION PER CYCLE WITH DONOR SPERM IS AS EFFICACEOUS AS 2 INSEMINATIONS

Purpose: To compare pregnancy rates per treatment cycle of artificial inseminations with donor sperm in patients receiving one versus two in seminations. Methods: Retrospective cross-sectioned analysis of 167 pa tients who underwent 869 cycles receiving one or two donor inseminatio ns were reviewed from 1987 through 1993 at our institution. Results: A total of 256 cycles with one donor insemination per cycle resulted in 21 pregnancies and a cycle of fecundity of 8.2%, and 613 cycles with two donor inseminations resulted in 35 pregnancies and a cycle fecundi ty of 5.7%. Life table and logistic cumulative probability analysis of pregnancy occurrence showed no difference between treatment groups. C onclusions: These data suggest there are no important clinical differe nces of cycle fecundity or cure rate in one versus two inseminations w ith donor sperm. Economic costs of two inseminations may not be justif ied.